AN AFFILIATE CHAPTER OF 

Sisters Network® Inc

A NATIONAL AFRICAN AMERICAN BREAST CANCER SURVIVORSHIP ORGANIZATION

SNHome

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New genes identified that regulate the spread of cancers

Researchers have discovered a new biological target for drugs to reduce the spread of tumours in cancer patients. The study with genetically modified mice found 23 genes that are involved in regulating the spread of cancers. The researchers showed that targeting one of these genes — Spns2 — led to a three-quarters reduction in tumor

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A novel cancer immunotherapy shows early promise in preclinical studies

Scientists report that GARP, a TGF-beta cell surface receptor, could be a novel diagnostic marker for breast, colon, and lung cancer. An antibody-based therapy targeting GARP prevented metastasis to the lung in a mouse model of breast cancer. Targeting GARP with an antibody could represent a novel addition to established immunotherapies that ‘wake up’ the

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Tucatinib (ONT-380) progressing in pivotal trial against HER2+ breast cancer

Twenty-seven percent of 50 heavily pretreated patients with stage IV HER2+ breast cancer saw clinical benefit from the drug Tucatinib (ONT-380) , with at least ‘stable disease’ at 24 or more weeks after the start of treatment. …read more Source:: http://feeds.sciencedaily.com       

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New insights into mechanisms of breast cancer development and resistance to therapy

Why does breast cancer develop and how come certain patients are resistant to established therapies? …read more Source:: http://www.medicalnewstoday.com       

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Role of common risk factors in ER-positive, ER-negative breast cancer

Researchers have examined the role of common risk factors in the development of ER-positive and ER-negative breast cancers. The study sheds new light on how a woman’s age, weight, and menopausal status affect her risk for breast cancer. …read more Source:: http://feeds.sciencedaily.com       

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New insights into mechanisms of breast cancer development and resistance to therapy

Why does breast cancer develop and how come certain patients are resistant to established therapies? Researchers have gained new insights into the molecular processes in breast tissue. They identified the tumor suppressor LATS as a key player in the development and treatment of breast cancer. …read more Source:: http://feeds.sciencedaily.com       

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Spread of triple-negative breast cancer could be halted with existing drug

Researchers find a class of drugs used to treat estrogen receptor-positive breast cancer might also reduce the spread of triple-negative breast cancer. …read more Source:: http://www.medicalnewstoday.com       

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New potential treatment for cancer metastasis identified

Breast cancer metastasis, the process by which cancer spreads, may be prevented through the new use of a class of drugs already approved by the US Food and Drug Administration, say investigators. …read more Source:: http://feeds.sciencedaily.com       

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